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ML-7 hydrochloride
CAS No. 110448-33-4
ML-7 hydrochloride( ML-7 HCl | ML-7 hydrochloride | ML-7 )
Catalog No. M10402 CAS No. 110448-33-4
ML-7 Hcl is a cell-permeable, potent, reversible, ATP-competitive, and selective inhibitor of myosin light chain kinase (Ki = 300 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 38 | In Stock |
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| 10MG | 61 | In Stock |
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| 25MG | 137 | In Stock |
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| 50MG | 257 | In Stock |
|
| 100MG | 334 | In Stock |
|
| 200MG | 434 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameML-7 hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionML-7 Hcl is a cell-permeable, potent, reversible, ATP-competitive, and selective inhibitor of myosin light chain kinase (Ki = 300 nM).
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DescriptionML-7 Hcl is a cell-permeable, potent, reversible, ATP-competitive, and selective inhibitor of myosin light chain kinase (Ki = 300 nM); also inhibt smooth-muscle myosin light chain kinase, protein kinase C (PKC) and cAMP-dependent protein kinase (PKA).
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In Vitro——
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In Vivo——
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SynonymsML-7 HCl | ML-7 hydrochloride | ML-7
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PathwayApoptosis
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TargetOther Targets
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RecptorPKA| PKC| MLCK
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Research AreaCardiovascular Disease
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Indication——
Chemical Information
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CAS Number110448-33-4
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Formula Weight452.74
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Molecular FormulaC15H18ClIN2O2S
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Purity>98% (HPLC)
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SolubilityDMSO: >43 mg/mL
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SMILESO=S(N1CCNCCC1)(C2=C3C=CC=C(I)C3=CC=C2)=O.[H]Cl
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Chemical Namehexahydro-1-[(5-iodo-1-naphthalenyl)sulfonyl]-1H-1,4-diazepine, monohydrochloride
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Luh Clara, et al. Journal of Neurochemistry (2010), 112(4), 1015-1025.
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